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    Oily injection: 80 mg/ml in 1-ml ampoule.
    Uses: treatment of severe P. falciparum malaria in areas where quinine is ineffective.
    Contraindications: first trimester of pregnancy.
    SKILLED TASKS. Dizziness may impair ability to perform skilled tasks, for example, operating machinery or driving.
    Treatment of severe P. falciparum malaria (in areas of quinine resistance), by intramuscular injection, ADULT and CHILD over 6 months, loading dose of 3.2 mg/kg, then 1.6 mg/kg daily until patient can tolerate oral medication or up to a maximum of 7 days; this is followed by a single dose of oral mefloquine 15 mg/kg (occasionally, 25 mg/kg if necessary) to effect a radical cure.
    ADMINISTRATION. Since small volumes are required for children, a 1-ml syringe should be used to ensure correct dosage.
    Adverse effects: headache, nausea, vomiting, abdominal pain, diarrhoea; dizziness, tinnitus, neutropenia, elevated liver enzyme values; cardiotoxicity (after high doses); neurotoxicity (in animal studies).Injection suppliers